Region One consists of 42 chapters that are divided into four sectors, each inspired by the four quadrants found in Star Trek. Each sector includes two states and is as follows:
Alpha Sector: Tennessee, Kentucky
Vice Admiral Ben C. Redding, Coordinator
Chapters of the Alpha Sector
SS Nikola Tesla SFR-005: Radcliff, KY
USS Aries NCC-71809-C: Grey, TN
USS Commonwealth NCC-74670: Richmond, KY
USS Constellation NCC-71855: Paducah, KY
USS Excelsior NCC 2000-B: Johnson City , TN
USS Explorer NCC-7121: Lewisburg, TN
USS Reprisal NCC-1896: Kingsport, TN
USS Tanasi NCC-81893: Newport, TN
USS Thunder NCC-42769: Shelbyville, KY
USS Yorktown NCC-97004: Kingsport, TN
Beta Sector: Indiana, Ohio
Rear Admiral Ron Novak, Coordinator
Chapters of the Beta Sector
USS Arizona NCC-71839: Magnolia , OH
USS Asgard NCC 72402: Columbus, OH
USS B Franklin NCC 72413: Columbus, OH
USS Columbia NCC 2049: Jeffersonville, IN
USS Gorkon NCC 40512: Flora, IN
USS Gungnir NCC 74209: Fortville, IN
USS Indiana NCC 79158: Indianapolis, IN
USS Jurassic NCC 3500: Wellington, OH
USS Lagrange NCC 3916-B: Cuyahoga Falls, OH
USS Liberator NCC 75008: Akron, OH
USS Moebius NCC 4744393: Lebanon, OH
USS Ohio NCC 75007: Barberton, OH
USS Renegade NCC 2547: Youngstown, OH
USS Tycho NCC 59325-A: Toledo, OH
Gamma Sector: North Carolina, South Carolina
Chapters of the Gamma Sector
USS Alaric NCC-503, Enka NC
USS Bonaventure NCC-102-A, Greensboro, NC
USS Charon NCC-80111, High Point, NC
USS Freedom NCC-71817, Parkton, NC
USS Hornet NCC-1714-D, Charlotte, NC
USS Kitty Hawk NCC-1659, Raleigh-Durham, NC
USS Ronald E McNair NCC-61809, Columbia, SC
USS Serenity NCC-97009, Greensboro, NC
USS Star League NCC-2101-A, Warrenville, SC
Delta Sector: Virginia, West Virginia
Captain Michael Tucci, Coordinator
Chapters of the Delta Sector
USS Appomattox NCC-75001, Lynchburg, VA
USS Belknap NCC-2501 , Arlington, VA
USS Decker NX-3030, Williamsburg, VA
USS Heimdal NCC-1793, Amherst, VA
USS Maat NCC-1794-A, Virginia Beach, VA
USS Mountaineer NCC-325306, Charleston, WV
USS Potomac NCC-2051, Alexandria, VA
USS Virginia NCC-71803, Waynesboro, VA
USS Yeager NCC-61893, Bluefield, WV